Noninvasive Prenatal Genetic Diagnosis

Congratulations to Prof. Bernard M. Dickens whose article, abstracted below, is now universally available.

Bernard M. Dickens, “Ethical and Legal Aspects of Noninvasive Prenatal Genetic Diagnosis,”   International Journal of Gynecology and Obstetrics 124.2 (2014): 181-184. online here.

Abstract:  The new technology that will allow genetic testing of a fetus within the first trimester of pregnancy by isolating cell-free fetal DNA (cffDNA) in the mother’s blood raises a range of ethical and legal issues. Considered noninvasive, this test is safe and reliable, and may avoid alternative genetic testing by amniocentesis or chorionic villus sampling, which risks causing spontaneous abortion. Ethical and legal issues of cffDNA testing will become more acute if testing expands to fetal whole-genome sequencing. Critical issues include the state of the science or diagnostic art; the appropriateness of offering the test; the implications of denying the test when it is available and appropriate; disclosure and counseling following test results; and management of patients’ choices on acquiring test results. A challenge will be providing patients with appropriate counseling based on up-to-date genetic knowledge, and accommodating informed patients’ legal choices.  Full text is online here.

Related Reading:
Rebecca J. Cook, “Stigmatized meanings of criminal abortion law,” chapter 16 of Abortion Law in Transnational Perspective: Cases and Controversies (University of Pennsylvania Press, 2014), 347-369, analyzes the decision of R.R. v. Poland (European Court of Human Rights),  which held that a woman in Poland should not have been denied access to genetic prenatal examinations which would have enabled her to decide whether or not to seek a legal abortion in Poland. Abstract of this chapter.   Book: Abortion Law in Transnational Perspective.   Libro: El aborto on el derecho transnacionalRR v Poland decision.

Bernard M. Dickens, “Preimplantation Genetic Diagnosis and ‘Saviour Siblings’International Journal of Gynecology and Obstetrics, Vol. 88, pp. 91-96, 2005  is online here.

76+ other articles on Ethical and Legal Issues in Reproductive Health are on our Program webpage here.

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